Springhill Group Medical – Medicine, Getting Personal

http://www.genengnews.com/gen-articles/medicine-getting-personal/4764/

Springhill Group Medical - Medicine, Getting Personal

No aspect of biopharma better epitomizes the goals and promise of delivering personalized medicine to treat and perhaps even cure intractable and disabling diseases than the emerging fields of cell and gene therapy. Adding to the excitement surrounding these technology-driven treatment approaches are their recent advance to the marketplace and increasing examples of progress in meeting clinical-scale production and regulatory challenges and achieving commercial success.

The progress and opportunities, obstacles and solutions, and optimistic projections and cautionary portents were all part of the science, technology, economic analysis, and insights presented, debated, and discussed at the recent “Phacilitate Cell & Gene Therapy Forum”.

Mahendra Rao, Ph.D., director of the NIH Center for Regenerative Medicine and head of the Laboratory of Stem Cell Biology at the NIH, led off the meeting and highlighted a key distinction from previous years: the growing number of commercial products now available for regenerative medicine.

Success begets new challenges, however, and Dr. Rao identified some of the issues this new reality is creating for young biotechnology companies. These may include how they ship their product, how to make a profit, how to deal with reimbursement and insurance issues, and how to manage competition.

The unique characteristics of cell therapies present new hurdles for this fledgling industry sector: individualized products prepared in small and even single doses; entirely or largely manual processes that need to be automated; and the challenges associated with reducing the cost of goods and leveraging economies of scale.

Other critical factors related to the actual products include storage, transport, time- and temperature-sensitivity, and time-out-of temperature specifications; chain of custody, overall quality control issues; and logistics considerations across the supply chain.

The main take-home message was to start thinking about factors related to commercialization of cell therapy product early in its development, and at every step along the way—including, for example, the potential impact of a change in a process, protocol, raw material, or analytical method.

Also emphasized by several presenters was the inevitable move toward automation, in the short-term at least aimed primarily at allogeneic cell therapies. Automated processing of cells and cell-based products will be essential for achieving optimal quality control and standardization, designing closed, disposable process streams, eliminating the risks associated with manual intervention and open systems, and reducing costs.

Moving to the Market

A roundtable discussion among a group of industry executives who have navigated the process of cell therapy commercialization focused on the question, “what does a commercially successful cell or gene therapy look like?”

One example was CartiStem®, developed by Medipost, and approved in 2011 in Korea for cartilage regeneration in the treatment of traumatic and degenerative osteoarthritis. The product has been used in about 250 patients but is not yet reimbursable. CartiStem is in Phase II trials in the U.S.

John Maslowski, vp scientific affairs at Fibrocell Science, which markets the aesthetic autologous human dermal fibroblast product azficel-T (LAVIV®) to improve the appearance of wrinkles, spoke about the labor-intensive nature of current autologous cell manufacturing processes.

Geoff MacKay, president and CEO of Organogenesis, described the company’s semi-automatic manufacturing process in place to produce its recently approved Gentuit™ product, composed of allogeneic human keratinocytes and fibroblasts, for oral tissue regeneration around teeth and implants.

For TiGenix, key hurdles in bringing to market its ChondroCelect® autologous cartilage product for the repair of single symptomatic defects have included lack of regulatory harmonization, and the need to reduce the cost and increase the effectiveness of therapy.

http://springhillmedgroup.com/

 

 

Springhill Medical Group – Korea

http://springhillgroupsite.weebly.com/1/post/2013/01/springhill-medical-group.html

 

 

Springhill Medical Group is a multi-specialty medical group providing primary and specialty care services with offices in Antioch, Brentwood and Pittsburg California.

  • Gerald Del Rio, M.D.  Internal Medicine/primary care & Pulmonary Medicine specialist
  • Siamak Elyasi, M.D.  Family practice/Primary care
  • Henry Gong, M.D.  Cardiology specialist
  • Hsien-Wen Hsu, M.D.  Pulmonary Medicine specialist
  • Irina Kolomey, D.O, Internal Medicine – Primary Care
  • Pragnesh Patel, M.D.   Endocrine specialist
  • Alejandro Prieto, M.D. Cardiology specialst
  • Michael Russell, M.D. Internal Medicine
  • Angelita Tangco, M.D.  Neurology specialist
  • Wengang Zhang, M.D.  Internal Medicine/Primary care


For more detailed information on all the physicians in Springhill Medical Group click on the Physician tab.

Springhill Medical Group is committed to providing comprehensive care 24 hours a day, 7 days a week in the office and at local hospitals, Sutter Delta Medical Center and John Muir Medical Center – Concord Campus. Once a patient has become established in the practice they have access to all the resources of the group including a live 24 hr answering service, on-call physicians and timely appointments. When your Springhill Physician is on vacation or out of the office another physician in the group will be able to access your electronic medical record and provide urgent care.

In 2006 Springhill Medical Group implemented a new Electronic Medical Record system will allows our physicians to access patient records from any office site.  We receive lab results electronically from John Muir Lab and Quest lab making the results avaiable to our physicians as soon as they are reported by the lab.

 

Springhill Groups Med: Warning! Cigarette Smoking is Dangerous to your Health!

http://www.ehow.com/boards/springhill-groups-med-warning-cigarette-smoking-is-dangerous-to-your-health-8922410/

Did you know that the leading cause of premature death in the United States is no other than cigarettes? A preventable death but it claims almost half a million lives each year. To the extent that the government required larger and more prominent warnings on cigarette packaging and advertisements as part of the strategy to help consumers quit smoking and prevent young people from starting. But despite of this it seems like tobacco users are not conscious about it.
Cigarette
The effects of cigarette smoking to human health are really serious and in fact deadly. There are approximately 4000 chemicals that are present in the chemical composition of cigarette and hundreds of which are toxic.

Smoking effects on the human body are destructive and widespread. The ingredients in cigarette affect everything from the internal functioning of the organs and target the efficiency of the body’s immune system. Smoking harms nearly every organ of the body. Smoking causes many diseases and reduces the health of smokers in general.
300px-Risks_form_smoking-smoking_can_damage_every_part_of_the_body
Here are some facts cigarette smoking can cause you. Toxic ingredients in cigarette smoke travel throughout the body, causing damage in several different ways. Carbon monoxide binds to hemoglobin in red blood cells, preventing affected cells from carrying a full load of oxygen. Cancer-causing agents (carcinogens) in tobacco smoke damage important genes that control the growth of cells, causing them to grow abnormally or to reproduce too rapidly. The carcinogen benzo(a)pyrene binds to cells in the airways and major organs of smokers. Smoking affects the function of the immune system and may increase the risk for respiratory and other infections. There are several likely ways that cigarette smoke does its damage. One is oxidative stress that mutates DNA, promotes atherosclerosis, and leads to chronic lung injury. Oxidative stress is thought to be the general mechanism behind the aging process, contributing to the development of cancer, cardiovascular disease, and COPD. The body produces antioxidants to help repair damaged cells. Smokers have lower levels of antioxidants in their blood than do nonsmokers. Smoking is associated with higher levels of chronic inflammation, another damaging process that may result in oxidative stress. Nicotine reaches the brain within 10 seconds after smoke is inhaled. It has been found in every part of the body and in breast milk.

Due to these facts, it is now known that cigarette smoking is deadly. An estimated 443, 000 deaths, or nearly one of every five years, each year has been noted in United States alone. It is more than the deaths caused by human immunodeficiency virus (HIV), illegal drug use, alcohol use, motor vehicle injuries, suicides, and murders combined. Smoking causes an estimated 90% of all lung cancer deaths in men and 80% of all lung cancer deaths in women. An estimated 90% of all deaths from chronic obstructive lung disease are caused by smoking.
C
This is very bothering. That is just some of the diseases that one can get from cigarette smoking. Smoking can also increased heart heath risks, cardiovascular disease, respiratory disease and cancer not to mention infertility, preterm delivery, stillbirth, low birth weight, and sudden infant death syndrome (SIDS).

Springhill Groups – Warning! Cigarette Smoking is Dangerous to your Health!

http://springhillgroupsite.bravesites.com/entries/news/springhill-groups-warning!-cigarette-smoking-is-dangerous-to-your-health!

Did you know that the leading cause of premature death in the United States is no other than cigarettes? A preventable death but it claims almost half a million lives each year. To the extent that the government required larger and more prominent warnings on cigarette packaging and advertisements as part of the strategy to help consumers quit smoking and prevent young people from starting. But despite of this it seems like tobacco users are not conscious about it.
Cigarette_smoking

The effects of cigarette smoking to human health are really serious and in fact deadly. There are approximately 4000 chemicals that are present in the chemical composition of cigarette and hundreds of which are toxic.

Smoking effects on the human body are destructive and widespread. The ingredients in cigarette affect everything from the internal functioning of the organs and target the efficiency of the body’s immune system. Smoking harms nearly every organ of the body. Smoking causes many diseases and reduces the health of smokers in general.
Smoke_2_brain
Here are some facts cigarette smoking can cause you. Toxic ingredients in cigarette smoke travel throughout the body, causing damage in several different ways. Carbon monoxide binds to hemoglobin in red blood cells, preventing affected cells from carrying a full load of oxygen. Cancer-causing agents (carcinogens) in tobacco smoke damage important genes that control the growth of cells, causing them to grow abnormally or to reproduce too rapidly. The carcinogen benzo(a)pyrene binds to cells in the airways and major organs of smokers. Smoking affects the function of the immune system and may increase the risk for respiratory and other infections. There are several likely ways that cigarette smoke does its damage. One is oxidative stress that mutates DNA, promotes atherosclerosis, and leads to chronic lung injury. Oxidative stress is thought to be the general mechanism behind the aging process, contributing to the development of cancer, cardiovascular disease, and COPD. The body produces antioxidants to help repair damaged cells. Smokers have lower levels of antioxidants in their blood than do nonsmokers. Smoking is associated with higher levels of chronic inflammation, another damaging process that may result in oxidative stress. Nicotine reaches the brain within 10 seconds after smoke is inhaled. It has been found in every part of the body and in breast milk.

Due to these facts, it is now known that cigarette smoking is deadly. An estimated 443, 000 deaths, or nearly one of every five years, each year has been noted in United States alone. It is more than the deaths caused by human immunodeficiency virus (HIV), illegal drug use, alcohol use, motor vehicle injuries, suicides, and murders combined. Smoking causes an estimated 90% of all lung cancer deaths in men and 80% of all lung cancer deaths in women. An estimated 90% of all deaths from chronic obstructive lung disease are caused by smoking.

This is very bothering. That is just some of the diseases that one can get from cigarette smoking. Smoking can also increased heart heath risks, cardiovascular disease, respiratory disease and cancer not to mention infertility, preterm delivery, stillbirth, low birth weight, and sudden infant death syndrome (SIDS).

Springhill Groups, Property Management

http://www.ehow.com/boards/springhill-group-property-management-8883910/

4879_1333106_201106111421590_md
Our Property Management division manages over $250 million of investment property in Queensland. We offer specialist property management services in the areas of commercial and passive residential property management in Brisbane, Queensland.   Our Property Management Capability allow The Pad Property Management to manage units, houses, unit/townhouse developments, larger scale residential accommodation/developments with locations from the CBD to inner north, inner west, inner south and inner west portfolios broadening our market, in addition to offering a diversity of housing choice and broad pricing point to capture a larger market.

Our sales team have over 15 years experience in the property industry with a strong commitment to results. We are experts in the residential property industry sector given our deep industry knowledge and understanding of the market. Some of our clients are now in the process of acquiring multiple investment properties and when coupled with our specialist Property Management team, our clients understand that their investment is well managed and will continue to derive a sustainable rental return in the future.

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Our Advisory business provides a specialist service to our Group in the areas of Development Management, Property Finance, Feasibility and Financial Analysis and General Advisory. Our founder has over 15 years experience working as an Advisor in Property to both Corporate and Government having practiced as a senior property and tax lawyer with Freehills Lawyers in both Melbourne and Brisbane as well as head of Property Advisory at PricewaterhouseCoopers in Brisbane and head of Structured Transactions and Advisory Services for CB Richard Ellis, Brisbane. Damian brings a strong legal and financial background to the Group and professional approach to dealings with clients.

Springhill medical: treat childhood obesity

http://springhillgroupsite.weebly.com/1/post/2012/12/springhill-medical-group-treat-childhood-obesity.html

You may find fat kids cutie ones but they may be starting to suffer from obesity.  Obesity is a serious medical condition that often leads to serious diseases.  Childhood obesity often carried out until adulthood, more health complications may occur.  And obesity plays a significant role in causing certain so called ‘adult ailments’ in our children such as high blood pressure and high cholesterol.

Childhood obesity is usually caused by eating too much and not getting enough exercise.  While there are some genetic and hormonal causes of childhood obesity, studies show the primary cause of children being overweight is due to lifestyle issues such as eating more calories than is needed to support their growing bodies, daily activities and metabolism.

All experts agreed that obesity is a health risk that may result to the following health problems for children.
Hypertension
Type 2 Diabetes
Orthopedic
Sleep
Depression
Asthma
Body Mass Index (BMI)
Height and BMI
Heredity
Signs of stress of weight on lower limbs and joints
Absence of logical thinking

How to treat obesity in children:

If your child has a weight problem you should a consult a doctor or nutritionist.  A healthy eating plan is strongly suggested. This is also to make sure that no serious health problems have developed.  Some parents delay this action in the hopes that the problem will just go away but this delay can cause more complications and illness and I will get worse.

Not only obesity can cause many health problems but it can also cause variety of emotional problems.  Their being obese can lower their self-esteem.  So do not make them feel bad more about themselves, they had enough from school instead just need to help them by developing healthy eating and exercise habits, and lots and lots of moral support.

You should be aware avoiding making their weight as an issue, if you will encourage him to focus on his weight tendency is that their self-esteem will suffer more rather it is best to show them how maintaining a healthy weight will lead to extra energy and fewer health problems.

Express your unconditional love. Remember to make them fell loved no matter what.  Overweight children need support, acceptance, and encouragement from their parents.

This is probably the most important and maybe the best solution.  Be a good role model. Parents are responsible for putting healthy foods in the kitchen at home, as well as leaving unhealthy foods on the grocery store shelves.  You cannot really blame the kids because you maybe is the problem.  Practice what you preach!  After all you are the one responsible of what food to put in the table.
Do not set food as rewards and put realistic goals.  It is also better if you will spend time together exercising, in this way he will be more excited to do it because he is with you.  Make them feel that you are together with this.

Springhill medical group – treat childhood obesity

http://springhillmedgroup.blogspot.com/

You may find fat kids cutie ones but they may be starting to suffer from obesity.  Obesity is a serious medical condition that often leads to serious diseases.  Childhood obesity often carried out until adulthood, more health complications may occur.  And obesity plays a significant role in causing certain so called ‘adult ailments’ in our children such as high blood pressure and high cholesterol.                                                                                       

Childhood obesity is usually caused by eating too much and not getting enough exercise.  While there are some genetic and hormonal causes of childhood obesity, studies show the primary cause of children being overweight is due to lifestyle issues such as eating more calories than is needed to support their growing bodies, daily activities and metabolism.

All experts agreed that obesity is a health risk that may result to the following health problems for children.

Hypertension

Type 2 Diabetes

Orthopedic

Sleep

Depression

Asthma

Body Mass Index (BMI)

Height and BMI

Heredity

Signs of stress of weight on lower limbs and joints

Absence of logical thinking

How to treat obesity in children:

If your child has a weight problem you should a consult a doctor or nutritionist.  A healthy eating plan is strongly suggested. This is also to make sure that no serious health problems have developed.  Some parents delay this action in the hopes that the problem will just go away but this delay can cause more complications and illness and I will get worse.

Not only obesity can cause many health problems but it can also cause variety of emotional problems.  Their being obese can lower their self-esteem.  So do not make them feel bad more about themselves, they had enough from school instead just need to help them by developing healthy eating and exercise habits, and lots and lots of moral support.

You should be aware avoiding making their weight as an issue, if you will encourage him to focus on his weight tendency is that their self-esteem will suffer more rather it is best to show them how maintaining a healthy weight will lead to extra energy and fewer health problems.

Express your unconditional love. Remember to make them fell loved no matter what.  Overweight children need support, acceptance, and encouragement from their parents.

This is probably the most important and maybe the best solution.  Be a good role model. Parents are responsible for putting healthy foods in the kitchen at home, as well as leaving unhealthy foods on the grocery store shelves.  You cannot really blame the kids because you maybe is the problem.  Practice what you preach!  After all you are the one responsible of what food to put in the table.

Do not set food as rewards and put realistic goals.  It is also better if you will spend time together exercising, in this way he will be more excited to do it because he is with you.  Make them feel that you are together with this.